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Study identifier: NCT07053436 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Horizon Two: HR NDMM (MMRC-100)

Condition: High Risk Newly Diagnosed Multiple Myeloma  ·  Sponsor: Multiple Myeloma Research Consortium

PhasePhase 2
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The Multiple Myeloma Research Consortium (MMRC) Horizon Two trial is a master protocol, multi-center, phase II randomized adaptive platform trial designed to efficiently evaluate multiple investigational therapies in high-risk newly diagnosed multiple myeloma patients using an integrated and patient-centric clinical research platform that enables longitudinal learning and sharing of knowledge and investigates multiple novel therapeutic strategies within one trial platform.

This description comes directly from the study's public registry record.

Talk to the study team

Jessica Vandermark  ·  2036520457  ·  vandermarkj@themmrf.org

Mercedes Martillo  ·  2036520457  ·  martillom@themmrf.org

Always discuss trial participation with your own doctor first.

Locations (7)

Emory UniversityAtlanta, Georgia, United StatesRecruiting
UChicago MedicineChicago, Illinois, United StatesRecruiting
Karmanos Cancer InstituteDetroit, Michigan, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Washington University Medical CenterSt Louis, Missouri, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
UNCChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07053436