← Eichor
Study identifier: NCT07053306 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia

Condition: Type 2 Diabetes  ·  Sponsor: The University of Texas Health Science Center at San Antonio

PhasePhase 1
Planned participants29
Who can joinAll sexes, 30 Years to 75 Years
Healthy volunteersNo

About this study

To examine the 2-HIT hypothesis that the SGLT2i-induced stimulation of EGP, lipolysis, and ketone production requires the combination of volume depletion plus insulinopenia in T2D individuals.

This description comes directly from the study's public registry record.

Talk to the study team

Ralph DeFronzo, MD  ·  210-567-6691  ·  defronzo@uthscsa.edu

Aurora Merovci, MD  ·  210-567-6691  ·  merovci@uthscsa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Texas Diabetes Institute/UHSan Antonio, Texas, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07053306