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Study identifier: NCT07050394 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Dose-Expansion Trial of Intravenous HNF4α srRNA for Unresectable or Metastatic Colorectal Cancer

Condition: Colorectal Cancer Metastatic · Colorectal Cancer Recurrent · Colorectal Cancer Stage IV  ·  Sponsor: Shanghai Changzheng Hospital

PhaseEARLY_Phase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a single-arm, open-label, exploratory clinical trial. Building on the previous dose-escalation trial, this dose-expansion trial aims to evaluate the safety and tolerability of intravenous monotherapy with CD-GA-102 or its combination with immunotherapy and other systemic treatments in patients with unresectable locally advanced or metastatic colorectal cancer, and to preliminarily explore its efficacy in treating colorectal cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Wen-Ping Xu, MD. PhD  ·  +862115026590980  ·  xwp198527@sina.com

Weifen Xie, MD. PhD  ·  +862113701682806  ·  weifenxie@medmail.com.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Changzheng HospitalShanghai, None Selected, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07050394