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Study identifier: NCT07048262 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)

Condition: Non-cystic Fibrosis Bronchiectasis  ·  Sponsor: CSL Behring

PhasePhase 2
Planned participants450
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This study is a phase 2b, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose range finding study designed to explore the efficacy, safety, and tolerability of 2 active treatment regimens of CSL787 (immunoglobulin G \[IgG\] inhalation solution) compared with placebo over a period of 6 to 12 months independent of the occurrence of pulmonary exacerbations. The primary aim of the study is to characterize the overall effect of CSL787 as well as the dose response of 2 active treatment regimens of inhaled CSL787 administered to participants with NCFB toward prolonging the TTF exacerbation.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Registration Coordinator  ·  +1 610-878-4697  ·  clinicaltrials@cslbehring.com

Always discuss trial participation with your own doctor first.

Locations (13)

The Prince Charles HospitalQueensland, AustraliaRecruiting
Westmead HospitalWestmead, AustraliaRecruiting
Fukuoka University Chikushi HopsitalChikushino-shi, JapanRecruiting
Kyusho Central Hospital of the Mutual Aid Association of Public School TeachersFukuoka, JapanRecruiting
Ibaraki Prefectural Central HospitalIbaraki, JapanRecruiting
Kazunori Tobino Iizuka HospitalIizuka-shi, JapanRecruiting
National Hospital Organization Minami Kyoto HospitalKyoto, JapanRecruiting
Matsusaka Municipal HospitalMie, JapanRecruiting
National Hospital Organization Kinki Chuo Chest Medical CenterOsaka, JapanRecruiting
Shimonoseki City HospitalShimonoseki-shi, JapanRecruiting
Japan Anti-Tuberculosis Association, Fukujuji HospitalTokyo, JapanRecruiting
Keio University HospitalTokyo, JapanRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07048262