Condition: Vaccination Varicella-zoster Virus · Immune-mediated Systemic Inflammatory Diseases · Sponsor: Assistance Publique - Hôpitaux de Paris
Patients with immune-mediated systemic inflammatory diseases (IMID) are at increased risk of shingles due to treatment-induced immunosuppression. In line with international recommendations, the French National Authority for Health (HAS) updated the varicella-zoster virus (VZV) vaccination strategy in March 2024. The HAS now recommends that immunocompromised people aged 18 and over be vaccinated with the recombinant VZV vaccine. However, due to the immunosuppressive treatment received, the vaccine response in MIMI patients is often suboptimal, and the protection induced by the herpes zoster vaccine in this context is unknown. The aim of our study is to determine the rate of anti-VZV seroconversion after vaccination with recombinant anti-VZV vaccine, in patients followed up for MIMI.
This description comes directly from the study's public registry record.
Tiphaine Goulenok, MD · 0140257289 · tiphaine.goulenok@aphp.fr
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| Hôpital Bichat | Paris, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07047053