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Study identifier: NCT07047014 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ischemic Stroke

Condition: Stroke, Ischemic · Medium Vessel Occlusions  ·  Sponsor: Beijing Tiantan Hospital

PhasePhase 3
Planned participants596
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Results from recent several trials provided data showing limits to the effectiveness of thrombectomy for ischemic stroke due to medium vessel occlusions.The benefit-risk profile of thrombolysis for these patients has never been investigated. We initiated a multicenter, prospective, randomized, open label, blinded-endpoint (PROBE) controlled trial to evaluate the efficacy and safety of tenecteplase (0.25mg/kg, maximum dose 25mg) compared to standard medical care for patients with acute ischemic stroke due to medium vessel occlusion (MeVO) within 4.5 to 24 hours from symptom onset.

This description comes directly from the study's public registry record.

Talk to the study team

Yunyun Xiong  ·  86-10-59978350  ·  xiongyunyun@bjtth.org

Ziqi Xu  ·  86-0571-87236666  ·  zyxuziqi@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (7)

Beijing tiantan hospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Jiuquan city people's hospitalJiuquan, Gansu, ChinaRecruiting
Xingtang People's HospitalShijiazhuang, Hebei, ChinaRecruiting
Jiyuan Traditional Chinese Medicine HospitalJiyuan, Henan, ChinaRecruiting
The first people hospital of lingbaoLingbao, Henan, ChinaRecruiting
Hai'an People's HospitalNantong, Jiangsu, ChinaRecruiting
The First Affiliated Hospital, School of Medicine, Zhejiang UniversityHangzhou, Zhejiang, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07047014