● Recruiting

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

Condition: Endometrial Cancer · Malignant Solid Tumour · Sponsor: AstraZeneca

PhasePhase 3

Planned participants800

Who can joinFemale, 18 Years to no upper limit

Healthy volunteersNo

About this study

This is a Phase III, 2-arm, randomized, open label, multicenter, global study assessing the efficacy and safety of puxitatug samrotecan compared to physician's choice of chemotherapy (doxorubicin or paclitaxel) in participants with B7-H4 selected advanced/metastatic EC that progressed following platinum based chemotherapy and anti-PD-1/anti-PD-L1 therapy.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center · 1-877-240-9479 · information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (317)

Research Site	Tucson, Arizona, United States	Not Yet Recruiting
Research Site	La Jolla, California, United States	Recruiting
Research Site	Los Angeles, California, United States	Withdrawn
Research Site	Orange, California, United States	Recruiting
Research Site	Washington D.C., District of Columbia, United States	Not Yet Recruiting
Research Site	Jupiter, Florida, United States	Recruiting
Research Site	Miami, Florida, United States	Not Yet Recruiting
Research Site	Miami, Florida, United States	Recruiting
Research Site	Miami Beach, Florida, United States	Recruiting
Research Site	New Port Richey, Florida, United States	Not Yet Recruiting
Research Site	Orlando, Florida, United States	Recruiting
Research Site	Tampa, Florida, United States	Not Yet Recruiting

+ 305 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07044336