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Study identifier: NCT07044050 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A First-in-human Study to Assess OT-C001 (Amplified/Activated Allogenic Natural Killer Cells) in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma

Condition: Diffuse Large B-cell Lymphoma With no Other Specification  ·  Sponsor: Emercell SAS

PhasePhase 1
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn the safety of OT-C001 and decide a good dose in treating relapsed or refractory diffuse large B-cell lymphoma patients. It will also learn about the preliminary activity of OT-C001. Participants will: Receive a short course of chemotherapy before OT-C001 treatment. During the study treatment, participants will recieve weekly dose of OT-C001 for 3 or 6 weeks. During the study period, participants will also receive another two drugs, rituximab and IL-2, to support OT-C001 treatment. Participants need to visit the clinic or may be hospitalized according to the study plan.

This description comes directly from the study's public registry record.

Talk to the study team

Erica Wang  ·  886 921 865 855  ·  e.wang@emercell.com

Bruno Piccolella  ·  +33 6 12 97 73 68  ·  bruno.piccolella@onward-therapeutics.com

Always discuss trial participation with your own doctor first.

Locations (1)

Saint-Eloi HospitalMontpellier, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07044050