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Study identifier: NCT07043608 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

Condition: Clear Cell Renal Cell Cancer (ccRCC) · Clear Cell Renal Carcinoma · Clear Cell Renal Cell Carcinoma Metastatic  ·  Sponsor: Kelly Fitzgerald, MD

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a single-institution, phase 2 trial of zanzalintinib plus investigator-choice bone-strengthening agent in patients with metastatic renal cell carcinoma (RCC) with bone metastases whose disease has advanced on 1-3 prior lines of therapy, including at least one immune oncology-based (IO) therapy in the adjuvant or first-line metastatic setting.

This description comes directly from the study's public registry record.

Talk to the study team

UCSF Genitourinary Oncology Clinical Trials Recruitment  ·  877-827-3222  ·  GUTrials@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California, San FranciscoSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07043608