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Study identifier: NCT07042139 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older

Condition: Distal Radius Fracture · Casting · Closed Reduction  ·  Sponsor: Tampere University Hospital

PhaseNA
Planned participants532
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

DISCLOSE trial is a randomized controlled trial including 532 participants with low-energy distal radius fractures. The primary objective is to evaluate whether casting without prior closed reduction is equivalent to casting following closed reduction with respect to wrist-related pain and disability, as measured by the Patient-Rated Wrist Evaluation (PRWE) score at 12 months, in patients aged 65 years or older with a displaced distal radius fracture. * Primary endpoint will be PRWE at 12 months * Follow-up visits are scheduled at 3 and 12 months. 5-year follow-up will be considered as an exploratory endpoint

This description comes directly from the study's public registry record.

Talk to the study team

Laura Kärnä, MD  ·  +3583311611  ·  laura.karna@pirha.fi

Ville Ponkilainen, MD, PhD  ·  +3583311611  ·  ville@disclosetrial.com

Always discuss trial participation with your own doctor first.

Locations (10)

Viborg regional HospitalViborg, DenmarkRecruiting
Tartu University HospitalTartu, EstoniaRecruiting
Tampere University HospitalTampere, Pirkanmaa, FinlandRecruiting
Helsinki University HospitalHelsinki, Uusimaa, FinlandRecruiting
Kanta-Häme Central HospitalHämeenlinna, FinlandRecruiting
Kuopio University HospitalKuopio, FinlandRecruiting
Oulu University HospitalOulu, FinlandRecruiting
Pori Central HospitalPori, FinlandNot Yet Recruiting
Turku University HospitalTurku, FinlandNot Yet Recruiting
Karolinska University HospitalStockholm, SwedenNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07042139