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Study identifier: NCT07041255 Synced from ClinicalTrials.gov · July 29, 2026
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Comparison of Cold and Hot Loop Resection Techniques for the Removal of Medium-sized Benign Colon Tumors

Condition: Benign Colon Tumors  ·  Sponsor: Pirogov Russian National Research Medical University

PhaseNA
Planned participants200
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

About this study

Widespread introduction of high-resolution videocolonoscopy into clinical practice has led to an increase in the detection of epithelial lesions of the colon, a significant portion of which are small (\<10 mm) and miniature (≤5 mm) lesions. According to the literature, 15.6-27% of colon lesions 6-9 mm in size and 4.4-10% of those ≤5 mm are high-risk lesions, i.e. they contain villous structures, foci of severe dysplasia or cancer. One of the methods for removing such lesions is the technique of cold loop polypectomy (CLP), i.e. mechanical removal of the polyp with a loop without the use of electric current. This method is common for colon lesions 4-9 mm in size. (For smaller lesions, a technically simple and effective method of removing them using biopsy forceps is most often used) Jung YS, Park JH, Kim HJ et al. Complete biopsy resection of diminutive polyps. Endoscopy 2013; 45: 1024-9). A number of studies have demonstrated the advantages of the CP technique over standard removal methods. "Cold" polypectomy reduces the incidence of complications associated with thermal effects on the mucous membrane and underlying tissues (Bo-In Lee. Polypectomy of Small Polyps: Technical Updates. IDEN 2016, 280-281). Not only the number of perforations and manifestations of postcoagulation syndrome is reduced (D. von Renteln1, H. Pohl. Polyp Resection - Controversial Practices and Unanswered Questions. Clin Transl Gastroenterol. 2017 Mar; 8(3): e76. doi: 10.1038/ctg.2017.6), but also delay…

This description comes directly from the study's public registry record.

Talk to the study team

Evgeny Fedorov  ·  +74999369980  ·  efedo@mail.ru

Evgeny Gorbachev  ·  +74999369980  ·  doc.fenix@mail.ru

Always discuss trial participation with your own doctor first.

Locations (1)

Evgeny GorbachevMoscow, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07041255