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Study identifier: NCT07039968 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Standard Dose Versus High Dose Stereotactic Spine Radiosurgery for Metastatic Spinal Neoplasms

Condition: Spinal Neoplasms  ·  Sponsor: National Taiwan University Hospital

PhasePhase 2
Planned participants196
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if a higher dose of Stereotactic Spine Radiosurgery (SSRS), an advanced radiation technique, is better for treating cancer that has spread to the spine (spinal metastases). The study will also learn about the safety of using a higher dose. The main questions it aims to answer are: Does a higher radiation dose lead to fewer treatment failures (meaning the tumor growing back or causing serious side effects) one year after treatment? What are the side effects associated with the high dose compared to the standard dose? How does each radiation dose affect a patient's pain and quality of life? Researchers will randomly assign participants (like a coin toss) to one of two groups to compare the outcomes: The Standard Dose Group: Will receive a single radiation treatment of 16 Gy. The High Dose Group: Will receive a single, more powerful radiation treatment of 20 Gy. Participants in this study will: Receive a single, one-time, highly-focused radiation treatment (SSRS) to the spinal tumor. Attend regular follow-up visits at the clinic for checkups and imaging scans (like MRI). Complete questionnaires about their pain levels and quality of life during these visits.

This description comes directly from the study's public registry record.

Talk to the study team

Feng-Ming Hsu, M.D., Ph.D  ·  886-2-23123456  ·  hsufengming@ntuh.gov.tw

Always discuss trial participation with your own doctor first.

Locations (2)

National Taiwan University HospitalTaipei, TaiwanRecruiting
National Taiwan University Cancer CenterTaipei, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT07039968