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Study identifier: NCT07039656 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Toripalimab Combined With Chemotherapy as Adjuvant Therapy for Non-small Cell Lung Cancer With or Without Prior Neoadjuvant Therapy

Condition: Stage IB-IIIB NSCLC · Stage IIB-III NSCLC  ·  Sponsor: Wen-zhao ZHONG

PhasePhase 2
Planned participants211
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a two-cohort, multicenter, Phase II study to evaluate the efficacy and safety of 3-4 cycles of toripalimab (JS001) plus chemotherapy followed by toripalimab maintenance treatment up to one year in participants with completely resected non-small cell lung cancer (NSCLC) stratified by prior neoadjuvant treatment status, as measured by disease-free survival (DFS) and overall survival (OS). Researchers will compare outcomes between two cohorts: 1. Cohort 1: Stage IB-IIIB participants following completely resection without neoadjuvant therapy; 2. Cohort 2: Stage IIB-III participants with non-MPR or MPR but lymph node positivity after neoadjuvant therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Wen-Zhao Zhong, MD  ·  86-13609777314  ·  13609777314@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Guangdong Provincial People's HospitalGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07039656