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Study identifier: NCT07039019 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of the Feasibility and Efficacy of PrednisonE for Non-specifiC pleuriTis

Condition: Pleuritis, Non-specific  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhaseEARLY_Phase 1
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This research study aims to evaluate whether corticosteroids help prevent the recurrence of pleural effusions in patients with non-specific pleuritis diagnosed through pleural biopsy. It can lead to recurrent fluid buildup in the lungs, causing discomfort and requiring additional medical interventions. There is no established treatment to prevent recurrence, and this study seeks to determine whether steroids reduce fluid buildup or cause complications. There will be two groups: one receiving corticosteroids (standard of care in the institution) and one not receiving corticosteroids (intervention group). The participation will last approximately 6 months, with in-person visits every 2 weeks for the first month, then monthly, along with possible telephone follow-ups. The study will monitor for pleural effusion recurrence, need for additional procedures, and potential side effects of corticosteroids. This is a pilot study. Although there are forty people expected to take part in this research study based on institutional data, the number of patients included in the study will be determined by the number of patients with non-specific pleuritis diagnosed during the study period.

This description comes directly from the study's public registry record.

Talk to the study team

Axel Duval, MD  ·  212-824-8546  ·  axel.duval@mountsinai.org

Always discuss trial participation with your own doctor first.

Locations (2)

Mount Sinai HospitalNew York, New York, United StatesRecruiting
Mount Sinai MorningsideNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07039019