● Recruiting

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

Condition: Solid Tumor Cancer · Locally Advanced · Metastatic Solid Tumors · Sponsor: Avenzo Therapeutics, Inc.

PhasePhase 1/Phase 2

Planned participants480

Who can joinAll sexes, 18 Years to 75 Years

Healthy volunteersNo

About this study

This study, the first clinical trial of AVZO-1418, aims to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, maximum tolerated dose, and antitumor activity of AVZO-1418 when administered intravenously as a monotherapy and potentially in combination therapy to patients with locally advanced or metastatic epithelial solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Medical Information · (858) 239-2944 · ClinicalTrials@avenzotx.com

Always discuss trial participation with your own doctor first.

Locations (18)

Avenzo Therapeutics Recruiting Site	Gilbert, Arizona, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Los Angeles, California, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Denver, Colorado, United States	Recruiting
Avenzo Therapeutics Recruiting Site	New Haven, Connecticut, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Washington D.C., District of Columbia, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Orlando, Florida, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Sarasota, Florida, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Tampa, Florida, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Atlanta, Georgia, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Boston, Massachusetts, United States	Recruiting
Avenzo Therapeutics Recruiting Site	New York, New York, United States	Recruiting
Avenzo Therapeutics Recruiting Site	Philadelphia, Pennsylvania, United States	Recruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07038343