Condition: Locally Advanced Non-Small Cell Lung Cancer · Thoracic Radiotherapy · Safety · Sponsor: JIANYANG WANG
Concurrent chemoradiotherapy (cCRT) is the standard treatment for patients with negative epidermal growth factor receptor (EGFR)-mutated unresectable locally advanced non-small cell lung cancer (LA-NSCLC). However, parts of patients only receive sequential chemoradiotherapy (sCRT) due to various reasons. This phase II study aimed to improve the outcomes of patients receiving sCRT by combining anti-angiogenesis therapy (Anlotinib) during radiotherapy course.We hypothesize that the combination of radiotherapy with anlotinib could improve the 2-year PFS rate from 35% with sCRT to 50. The accrual target was 44 patients.
This description comes directly from the study's public registry record.
jianyang wang, MD · +86-13810095191 · pkucell@163.com
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| Department of Radiation Oncology,Cancer Institute and Hospital,Chinese | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07037680