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Study identifier: NCT07033819 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant Treatment of Ovarian Cancer With Fuzuloparib in Combination With Apatinib

Condition: Ovarian Cancer  ·  Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

PhasePhase 2
Planned participants48
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

In this study, investigators propose to use fuzuloparib and apatinib as neoadjuvant therapy for Homologous recombination deficiency (HRD)positive advanced ovarian cancer patients, aiming to explore the efficacy and safety of this 'de-chemotherapy' regimen as neoadjuvant therapy for advanced ovarian cancer, and to conduct genetically related subgroup analyses, to guide the precision therapy and provide a new therapeutic option for HRD-positive patients with advanced ovarian cancer. To provide a new treatment option In order to increase the R0 resection rate of surgery and reduce chemotherapy resistance, thus improving the prognosis and prolonging the survival of patients.

This description comes directly from the study's public registry record.

Talk to the study team

Bin Li Bin Li, PhD  ·  86+13801364117  ·  libin@cicams.ac.cn

Always discuss trial participation with your own doctor first.

Locations (1)

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07033819