Condition: Leukemia, Myelomonocytic, Chronic · Sponsor: Theradex
The goal of this clinical trial is to learn if pacritinib works better than hydroxyurea to treat advanced proliferative chronic myelomonocytic leukemia in adults. The main questions it aims to answer are: * Does pacritinib improve disease control compared to hydroxyurea? * What medical problems do participants have when taking pacritinib or hydroxyurea? Researchers will compare pacritinib to hydroxyurea to see if pacritinib is more effective and better tolerated in people with advanced proliferative chronic myelomonocytic leukemia. Participants will be randomly assigned to receive either pacritinib twice a day or hydroxyurea for up to 48 weeks. After treatment ends, participants will be followed for up to one year.
This description comes directly from the study's public registry record.
Zach Albaugh · zalbaugh@theradex.com
Melissa Fischer · mfischer@mdsmpn.org
Always discuss trial participation with your own doctor first.
| Moffitt Cancer Center | Tampa, Florida, United States | Recruiting |
| Winship Cancer Institute at Emory | Atlanta, Georgia, United States | Recruiting |
| Mayo Clinic Rochester | Rochester, Minnesota, United States | Recruiting |
| MD Anderson Cancer Center | Houston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07033598