Condition: Early Alzheimer's Disease · Sponsor: Merck Sharp & Dohme LLC
Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD). AD is a type of dementia that can cause loss of memory, communication (such as speech), and decision-making skills. It can limit a person's ability to do daily tasks. MK-2214 is a study treatment designed to slow down AD. The goals of the study are to learn: * If MK-2214 slows the spread of tau in the brain compared to placebo. Tau is a protein that accumulates in AD \& damages brain cells. A placebo looks like the study treatment but has no study treatment in it. Using a placebo helps researchers better understand the effects of a study treatment. * About the safety of MK-2214 and if people tolerate it
This description comes directly from the study's public registry record.
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| Irvine Clinical Research ( Site 1041) | Irvine, California, United States | Recruiting |
| Healthy Brain Clinic ( Site 1005) | Long Beach, California, United States | Recruiting |
| Inglewood Clinical ( Site 1062) | Los Angeles, California, United States | Recruiting |
| Anderson Clinical Research ( Site 1024) | Redlands, California, United States | Recruiting |
| UCSF Memory and Aging Center ( Site 1031) | San Francisco, California, United States | Recruiting |
| Syrentis Clinical Research ( Site 1001) | Santa Ana, California, United States | Recruiting |
| Yale University, Alzheimer's Disease Research Unit ( Site 1059) | New Haven, Connecticut, United States | Recruiting |
| JEM Research Institute ( Site 1046) | Atlantis, Florida, United States | Recruiting |
| Neuropsychiatric Research Center of Southwest Florida ( Site 1003) | Fort Myers, Florida, United States | Recruiting |
| K2 Medical Research ( Site 1047) | Maitland, Florida, United States | Recruiting |
| ClinCloud LLC ( Site 1039) | Melbourne, Florida, United States | Recruiting |
| Indago Research and Health Center Inc ( Site 1044) | Miami Lakes, Florida, United States | Recruiting |
+ 67 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07033494