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Study identifier: NCT07033416 Synced from ClinicalTrials.gov · July 28, 2026
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A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder

Condition: Training for Cocaine Use Disorder  ·  Sponsor: ASST Fatebenefratelli Sacco

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to investigate if the intervention "Approach Bias Modification" (ABM) can low cocaine craving in people with Cocaine Use Disorder (CUD). The main question this clinical trial aims to answer is how many days participants can be in abstinence from cocaine after 4 ABM sessions. ABM is a computerised training aiming to train the participants to: * avoid drug-related images by pushing a joystick which causes the image to disappear; * approach positive images by pulling a joystick which causes the image to expand. Researchers will compare participants treated with ABM to those who receive Treatment As Usual (TAU) condition to see if ABM training for CUD is more effective in increasing the number of abstinent days. * Participants will attend 1 ABM session per week for a total of 4 sessions, each lasting 15 minutes. * Both cocaine and non-cocaine positive images relative to the subjective values or interests (i.e. effects, sport, music, nature, work, etc.) are presented to the participant, in portrait or landscape orientation. * Participants are instructed to push the joystick if the image is portrait-oriented (cocaine-related images) or to pull the joystick if it is landscape-oriented (positive images). * At 1 and 3-month-follow up, participants will complete self-report questionnaires to measure abstinence days and describe the effect of ABM on cocaine use, dependence symptoms, and approach bias.

This description comes directly from the study's public registry record.

Talk to the study team

Stefania Cheli, PhD  ·  +390250319643  ·  stefania.cheli@asst-fbf-sacco.it

Always discuss trial participation with your own doctor first.

Locations (1)

Struttura Semplice Servizio DipendenzeMilan, Milano, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07033416