Condition: Obsessive - Compulsive Disorder · Sponsor: Shanghai Mental Health Center
The goal of this clinical trial is to evaluate the efficacy and influencing factors of the combination of the anterior limb of internal capsule and nucleus accumbens (ALIC-NAc) deep brain stimulation (DBS) in patients with treatment-refractory obsessive-compulsive disorder (OCD). The main questions it aims to answer is: Does the timing of DBS activation (at 1, 2, or 3 months post-surgery) affect the reduction rate in Y-BOCS scores? Researchers will compare three groups-DBS activated at 1, 2, and 3 months post-surgery-to determine whether earlier or later stimulation leads to greater symptom improvement. Participants will: * Undergo surgical implantation of an intracranial neurostimulation system targeting ALIC-NAc * Be randomly assigned to one of three DBS activation timing groups * Receive regular clinical assessments over a 6-month follow-up period after activation
This description comes directly from the study's public registry record.
Zhen Wang, Ph.D, M.D · +8602164387250 · wangzhen@smhc.org.cn
Always discuss trial participation with your own doctor first.
| First Affiliated Hospital of Jinan University | Guangzhou, Guangdong, China | Recruiting |
| The First Hospital of Hebei Medical University | Shijiazhuang, Hebei, China | Recruiting |
| The Second Affiliated Hospital of Xinxiang Medical College | Xinxiang, Henan, China | Recruiting |
| The First Affiliated Hospital of Nanchang University | Nanchang, Jiangxi, China | Recruiting |
| The First Affiliated Hospital of Shanxi Medical University | Taiyuan, Shanxi, China | Recruiting |
| the Third Hospital of Mianyang | Mianyang, Sichuan, China | Recruiting |
| Shanghai Mental Health Center | Shanghai, China | Recruiting |
| Huashan Hospital | Shanghai, China | Recruiting |
| Tianjin Huanhu Hospital | Tianjin, China | Recruiting |
| Tianjin Anding Hospital | Tianjing, China | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07031544