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Study identifier: NCT07030569 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

Condition: Radiomic · Radiomics · Breast Cancer Metastatic  ·  Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

PhaseN/A
Planned participants500
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

RADIOSPHER2 study is a monocentric, retrospective, observational study aiming at identifying a radiomics signature able to predict HER2 expression (0 vs low vs overexpression) and trastuzumab deruxtecan efficacy in metastatic breast cancer patients. The study also encompasses translational analyses and inter-modal correlations in order to provide novel insights about HER2 spatial and temporal heterogeneity, at the macroscopic and microscopic levels.

This description comes directly from the study's public registry record.

Talk to the study team

Claudio Vernieri, MD, PhD  ·  +390223903066  ·  claudio.vernieri@istitutotumori.mi.it

Leonardo Provenzano, MD  ·  +390223903066  ·  leonardo.provenzano@istitutotumori.mi.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione IRCCS Istituto Nazionale TumoriMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07030569