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Study identifier: NCT07029399 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

Condition: HR+ Breast Cancer · Triple Negative Breast Cancer (TNBC) · CCNE1 Amplified Advanced Solid Tumors  ·  Sponsor: NiKang Therapeutics, Inc.

PhasePhase 1
Planned participants361
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this open-label dose escalation and expansion study is to evaluate the safety and tolerability of NKT5097 in adults with advanced/metastatic tumors (emphasis on breast cancer and solid tumors with CCNE1 amplification). Main questions to answer include: * What is the recommended dose for expansion and/or Phase 2, for both monotherapy and in combination with ET * What medical issues/symptoms do participants experience when taking NKT5097 as monotherapy as well as in combination with ET

This description comes directly from the study's public registry record.

Talk to the study team

Sponsor Contact  ·  302-596-8654  ·  clinicaltrials@nikangtx.com

Always discuss trial participation with your own doctor first.

Locations (18)

City of HopeDuarte, California, United StatesRecruiting
UC San Diego Moores Cancer CenterLa Jolla, California, United StatesRecruiting
Sarah Cannon Research Institute at HealthONEDenver, Colorado, United StatesRecruiting
Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
SCRI Florida Cancer Specialists - SarasotaSarasota, Florida, United StatesRecruiting
University of IowaIowa City, Iowa, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
South Texas Accelerated Research Therapeutics (START) MidwestGrand Rapids, Michigan, United StatesRecruiting
Washington UniversitySt Louis, Missouri, United StatesRecruiting
Comprehensive Cancer Centers of NevadaLas Vegas, Nevada, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting
UPMC Hillman Cancer CenterPittsburgh, Pennsylvania, United StatesRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07029399