Condition: Obesity · Visceral Adipose Tissue · White Adipose Tissue Inflammation · Sponsor: Nantes University Hospital
Disruption of white adipose tissue (WAT) homeostasis during obesity is central to the development of associated cardiometabolic complications. Dietary supplementation with oleic acid in obese patients can limit these complications. Experimental data, obtained in preclinical models, suggest that the beneficial effects of oleic acid may protect the TAB by increasing cholesterol esterification. The NAMICO study aims to test this hypothesis using TAB biopsies collected from obese patients undergoing bariatric surgery who had previously undergone dietary enrichment with either a conventional oil or an oil rich in oleic acid.
This description comes directly from the study's public registry record.
Marie De Montrichard, PH · +332 40 08 30 22 · marie.dabadie@chu-nantes.fr
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| CHU de Nantes | Nantes, France, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07027033