Condition: ACS (Acute Coronary Syndrome) · Myocardial Infarction (MI) · Myocardial Inflammation · Sponsor: University Hospital Centre Mother Teresa
This prospective observational study aims to evaluate the prognostic significance of the neutrophil-to-lymphocyte ratio (NLR) as a predictor of mortality in patients following an episode of Acute Coronary Syndrome (ACS). Despite advancements in interventional cardiology and medical therapy, mortality remains significant in post-ACS patients, and early risk stratification is essential for optimizing outcomes. Recent studies have suggested that systemic inflammatory markers, such as NLR, are associated with adverse cardiovascular events. It is an easily obtainable and cost-effective laboratory parameter derived from a routine complete blood count. However, its value as an independent predictor of mortality post-ACS has not yet been fully established in our population. The study will include patients aged, admitted with a confirmed diagnosis of ACS (STEMI or Non-STEMI) and treated with percutaneous coronary intervention (PCI). NLR values will be measured from the first blood draw upon hospital admission, 24 and 48 hours post PCI. Patients will be followed up for up to 6 months after discharge through telephone interviews . First, primary outcomes of the study will be the association between NLR values and mortality (all cause mortality and cardiovascular mortality), MACE (MACE was defined as the composite of all-cause mortality, cardiac death, unplanned revascularization, non-fatal myocardial infarction that was attributable and not related to stent failure or unplanned revas…
This description comes directly from the study's public registry record.
Martiola Kola, MD · 003553410998 · martiola.kola@gmail.com
Andi Rroku, MD · +4930450613689 · andi.rroku@dhzc-charite.de
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| Faculty of Medicine Tirana | Tirana, Albania | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07026708