Condition: Endometrial Cancer · Sponsor: National Institute of Cancerología
Background: Endometrial cancer is one of the diseases linked to obesity in women. In Mexico, about 7.6 women out of every 100,000 are diagnosed with this type of cancer, and nearly three-quarters of these women have obesity. Many women with endometrial cancer also have a condition called sarcopenic obesity, where muscle loss happens but might not be easy to identify. Researchers believe that certain molecules in the blood could help identify the health of muscles. Exercise helps muscles stay strong and healthy by affecting these molecules. For women with cancer, staying active can help maintain muscle mass, which is important for better recovery and health outcomes. This project focuses on an exercise program for women with locally advanced endometrial cancer who will be treated surgically at the National Cancer Institute of Mexico (INCan). What We Think Will Happen: Women with endometrial cancer who participate in a program combining physical activity and healthy eating will gain more muscle strength and function compared to those who don't exercise. We expect these changes to be connected to healthier levels of certain molecules in the blood, showing less muscle breakdown and less inflammation. We also believe these women will have better control of blood sugar and fats. Our Main Goal: To find out how physical activity and diet affect muscle health and metabolism in women with endometrial cancer, and to compare these changes to women who don't participate in the exerci…
This description comes directly from the study's public registry record.
Denisse Castro Eguiluz, PhD · +52 55 4194 0650 · adcastro@secihti.mx
Julissa Luvián Morales, PhD · +52 556 934 7316 · juli.luvian.morales@gmail.com
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| Instituto Nacional de Cancerología | México, Tlalpan, Mexico | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07025213