← Eichor
Study identifier: NCT07025148 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)

Condition: Coronary Arterial Disease (CAD) · Percutaneous Coronary Intervention (PCI)  ·  Sponsor: University of Florida

PhasePhase 4
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary aim of this study is to investigate the PD effects of switching from standard-dose clopidogrel dose to low-dose prasugrel versus continuing standard-dose clopidogrel in patients at dual-risk (HBR defined as the HBR-ARC criteria and HIR defined as ABCD-GENE score ≥10) following PCI. We hypothesize that in patients at dual-risk, switching from standard-dose clopidogrel to low-dose prasugrel will be superior to continuing standard-dose clopidogrel in terms of platelet reactivity.

This description comes directly from the study's public registry record.

Talk to the study team

Luis Ortega-Paz, MD, PhD  ·  904-244 2060  ·  Luis.Ortega@jax.ufl.edu

Andrea Burton, MPH, CCRP  ·  904-244-5617  ·  Andrea.Burton@jax.ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Florida HealthJacksonville, Florida, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07025148