● Recruiting

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort

Condition: Chronic Kidney Disease · Sponsor: AstraZeneca

PhasePhase 1

Planned participants124

Who can joinAll sexes, 18 Years to 75 Years

Healthy volunteersYes

About this study

This study will evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single ascending doses (SAD) and multiple ascending doses (MAD) of AZD4248 administered as an oral solution and intravenous (IV) infusion. Additionally, the study investigates the non-interventional feasibility of home measurement of serum creatinine in participants with diabetic kidney disease (DKD).

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center · 1-877-240-9479 · information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (5)

Research Site	Glendale, California, United States	Recruiting
Research Site	Chicago, Illinois, United States	Recruiting
Research Site	Ann Arbor, Michigan, United States	Active Not Recruiting
Research Site	Saint Paul, Minnesota, United States	Recruiting
Research Site	San Antonio, Texas, United States	Recruiting

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Source record: clinicaltrials.gov/study/NCT07024823