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Study identifier: NCT07023484 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Personalized Timing of Interval Debulking Surgery in Advanced Ovarian Cancer

Condition: Ovarian Cancer · Fallopian Tube Cancer · Primary Peritoneal Carcinoma  ·  Sponsor: The University of Hong Kong

PhasePhase 2
Planned participants126
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

About 70% of epithelial ovarian cancer patients are diagnosed at advanced stage. When primary optimal surgery is not possible, neoadjuvant chemotherapy will followed by interval debulking surgery is one treatment option. However, there is no consensus on the optimal timing of the surgery. CA125 is a well-known tumor marker in ovarian cancer. Its kinetic change has been proven to correlate with the patients' response to chemotherapy and chance of optimal resection. This study aims to utilize the kinetic change of CA125 to customize the timing of surgery for individual patients and compare this with the standard clinical practice.

This description comes directly from the study's public registry record.

Talk to the study team

Lesley Lau, MPhil  ·  +852 22554265  ·  lsk382@hku.hk

Iris Tang  ·  +852 22554265  ·  iristwk@hku.hk

Always discuss trial participation with your own doctor first.

Locations (6)

Sun Yat-sen University Cancer CenterGuangzhou, ChinaNot Yet Recruiting
The University of Hong Kong - Shenzhen HospitalShenzhen, ChinaNot Yet Recruiting
Pamela Youde Nethersole Eastern HospitalPamela YChai Wan, Hong KongNot Yet Recruiting
Queen Mary Hospital, Department of Clinical OncologyHong Kong, Hong KongNot Yet Recruiting
The University of Hong Kong, Department of Obstetrics and GynaecologyHong Kong, Hong KongRecruiting
United Christian HospitalKwun Tong, Hong KongNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07023484