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Study identifier: NCT07023289 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

Condition: Colorectal Cancer  ·  Sponsor: AbbVie

PhasePhase 2
Planned participants140
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess change in disease activity when telisotuzumab adizutecan is given alone compared to standard of care (SOC) given alone. Telisotuzumab adizutecan is an investigational drug being developed for the treatment of CRC. This study will be divided into two groups called treatment arms. In arm 1 participants will receive telisotuzumab adizutecan alone. In arm 2 participants will receive SOC alone. Approximately 140 adult participants with CRC will be enrolled in the study in 45 sites worldwide. In arm 1, participants will receive intravenous (IV) doses of telisotuzumab adizutecan alone. In arm 2 Participants will receive SOC alone. The study will run for a duration of approximately 51 months. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at an approved institution (hospital or clinic). The effect of the treatment will be frequently checked by medical assessments, blood tests, questionnaires and side effects.

This description comes directly from the study's public registry record.

Talk to the study team

ABBVIE CALL CENTER  ·  844-663-3742  ·  abbvieclinicaltrials@abbvie.com

Always discuss trial participation with your own doctor first.

Locations (48)

Clearview Cancer Institute - Huntsville - Cci Drive /ID# 278621Huntsville, Alabama, United StatesRecruiting
Providence Medical Foundation - Fullerton /ID# 274207Fullerton, California, United StatesRecruiting
USC Norris Comprehensive Cancer Center /ID# 274550Los Angeles, California, United StatesRecruiting
Mayo Clinic Hospital Jacksonville /ID# 274472Jacksonville, Florida, United StatesRecruiting
Moffitt Cancer Center /ID# 274372Tampa, Florida, United StatesRecruiting
University of Chicago Medical Center /ID# 274742Chicago, Illinois, United StatesRecruiting
Johns Hopkins Hospital /ID# 275645Baltimore, Maryland, United StatesRecruiting
Massachusetts General Hospital /ID# 273608Boston, Massachusetts, United StatesRecruiting
University of Michigan Health System - Ann Arbor /ID# 273511Ann Arbor, Michigan, United StatesRecruiting
Scri Minnesota Oncology Hematology, P.A. /ID# 275149Minneapolis, Minnesota, United StatesRecruiting
Mayo Clinic-Rochester /ID# 273508Rochester, Minnesota, United StatesRecruiting
Northwell Health Center for Advanced Medicine. /ID# 275331Lake Success, New York, United StatesRecruiting

+ 36 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07023289