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Study identifier: NCT07020312 Synced from ClinicalTrials.gov · July 28, 2026
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Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

Condition: Anterior Cruciate Ligament Reconstruction · Total Hip Arthroplasty (THA) · Total Knee Arthroplasty  ·  Sponsor: Rush University Medical Center

PhasePhase 2
Planned participants240
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

After orthopedic surgeries like knee or hip replacement, some patients struggle to fully activate their muscles due to a condition called Arthrogenic Muscle Inhibition (AMI). AMI can slow recovery and make physical therapy less effective. This clinical trial is testing whether a special type of brain training-called neurofeedback visualization training-can help improve muscle activation and speed up recovery. In this study, patients will receive standard physical therapy after surgery. Half of them will also use a device that helps them "visualize" exercises while wearing a cap that reads brain signals (EEG). The cap tracks brain activity when patients imagine doing specific movements. A computer then shows a virtual avatar performing the movements, giving feedback in real time-like a video game controlled by the brain. The study includes patients recovering from one of four surgeries: 1. Anterior cruciate ligament reconstruction (ACLR) 2. Total knee arthroplasty (TKA) 3. Total hip arthroplasty (THA) 4. Hip arthroscopy (HA) for femoroacetabular impingement (FAI) The goal is to see if this training improves muscle strength, movement, and daily function more than standard therapy alone. The study will take place at Rush University Medical Center in Chicago and enroll 240 adults, with 60 patients per type of surgery. Each participant will be followed for up to 6 months after surgery and complete strength tests, movement assessments, and questionnaires about their recovery. …

This description comes directly from the study's public registry record.

Talk to the study team

Brian Forsythe, MD  ·  708-236-2782  ·  Brian.forsythe@rushortho.com

Always discuss trial participation with your own doctor first.

Locations (1)

Rush University Medical CenterChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07020312