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Study identifier: NCT07020221 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

Condition: Pancreatic Ductal Adenocarcinoma · Non Small Cell Lung Cancer · Colorectal Cancer  ·  Sponsor: Verastem, Inc.

PhasePhase 1/Phase 2
Planned participants295
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will assess the safety and efficacy of VS-7375 alone and in combination in patients with advanced solid tumors harboring a KRAS G12D-mutation.

This description comes directly from the study's public registry record.

Talk to the study team

Verastem Call Center  ·  1 781 292 4204  ·  clinicaltrials@verastem.com

Always discuss trial participation with your own doctor first.

Locations (14)

Cedars-Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Johns Hopkins UniversityBaltimore, Maryland, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesRecruiting
Washington University School of MedicineSt Louis, Missouri, United StatesRecruiting
Laura & Isaac Perlmutter Cancer Center at NYU LangoneNew York, New York, United StatesRecruiting
Univ of Pennsylvania, Abramson Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
Huntsman Cancer InstituteSalt Lake City, Utah, United StatesRecruiting
University of VirginiaCharlottesville, Virginia, United StatesRecruiting
Virginia Cancer SpecialistsFairfax, Virginia, United StatesRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07020221