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Study identifier: NCT07018752 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Platform Trial Evaluating New Drugs or Combination in R/R Peripheral T-cell Lymphomas

Condition: Peripheral T Cells Lymphoma (PTCL)  ·  Sponsor: The Lymphoma Academic Research Organisation

PhasePhase 1/Phase 2
Planned participants49
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a platform trial for the evaluation of new drugs or combination of drugs in relapsed or refractory peripheral T-cell lymphomas. The objective of the study is to generate exploratory data on new drugs or combination of drugs to treat refractory/relapse peripheral T-cells lymphoma to better identify the population of interest and design future correct clinical trials. Primary objectives of the different sub-studies : * phase 1 sub-studies: determine the safety and tolerability of escalating doses of the sub-study treatment * phase 2 sub-studies: identify drugs that will improve significantly the outcome in target patients Secondary objectives of both sub-studies: analyze the response rate, the clinical benefit rate, the progression-free survival, the duration of response, the time to next treatment or death, the overall survival, the rate of transplantation following study treatment and the safety profile of the drugs used

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Project Manager  ·  +33 4 72 66 93 33  ·  platform@lysarc.org

Always discuss trial participation with your own doctor first.

Locations (20)

Institut d'Hématologie de Basse Normandie - Service Hématologie (CHU Hôpital Côte de Nacre)Caen, FranceRecruiting
CHU Estaing - Service Thérapie Cellulaire et Hématologie CliniqueClermont-Ferrand, FranceNot Yet Recruiting
Hôpital Henri Mondor - Unité Hémopathies LymphoïdesCréteil, FranceRecruiting
CHU Dijon Bourgogne - Service Hématologie CliniqueDijon, FranceRecruiting
CHU de Grenoble - Service HématologieLa Tronche, FranceNot Yet Recruiting
CH du Mans - Centre de Cancérologie de la Sarthe - Service HématologieLe Mans, FranceNot Yet Recruiting
CHU de Lille - Hôpital Claude Huriez - Service des Maladies du SangLille, FranceRecruiting
Institut Paoli Calmettes - Service HématologieMarseille, FranceNot Yet Recruiting
CHU de Montpellier - Département d'Hématologie CliniqueMontpellier, FranceRecruiting
CHU de Nantes - Service HématologieNantes, FranceRecruiting
Hôpital Necker - Service Hématologie AdultesParis, FranceRecruiting
CHU de Bordeaux - Hôpital Haut-Lévêque - Centre François Magendie - Service d'Hématologie et Thérapie CellulairePessac, FranceNot Yet Recruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07018752