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Study identifier: NCT07017946 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Intestinal Microbiome Transplant in ALS

Condition: Amyotrophic Lateral Sclerosis ALS  ·  Sponsor: Duke University

PhasePhase 1/Phase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a 24-week study of intestinal microbiome transplant in people with ALS. All participants will be evaluated clinically in person for 4 visits. Blood and mailed/ fresh stool samples will also be collected. Blood samples will be used to determine changes in neurofilament light chain over time. Stool samples will be processed for microbiome analysis. Participants will have phone visits to further evaluate safety and tolerability. They will then undergo antibiotic conditioning and a standard bowel preparation before being assigned to the investigational product, MTP-101C .

This description comes directly from the study's public registry record.

Talk to the study team

Richard Bedlack, MD, PhD  ·  919-613-2681  ·  ALSresearch@duke.edu

Michelle Ward, RN  ·  919-613-2681  ·  ALSresearch@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07017946