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Study identifier: NCT07014150 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant Therapy of Iparomlimab and Tuvonralimab Combined With Lenvatinib for Hepatocellular Carcinoma

Condition: Hepatocellular Carcinoma Resectable  ·  Sponsor: Peking Union Medical College Hospital

PhasePhase 2
Planned participants33
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if the neoadjuvant therapy of iIparomlimab and Tuvonralimab plus lenvatinib works to treat hepatocellular carcinoma(HCC) patients with high risk of recurrence. It will also learn about the safety of the combination of iIparomlimab and Tuvonralimab plus lenvatinib. The main questions it aims to answer are: Does the combination therapy improve the major pathological response rate and reduce the risk of disease recurrence or progression in HCC patients? What medical problems do participants have when taking this combination regimen? Researchers will compare this combination to previous studies to evaluate its efficacy and safety in managing HCC. Participants will: Take iIparomlimab and Tuvonralimab every 3 weeks for three times and lenvatinib everyday for 9 weeks. Visit the clinic once every 3 weeks for checkups and tests Keep a diary of their symptoms and the number of times when taking the combination regimen.

This description comes directly from the study's public registry record.

Talk to the study team

Chengjie Li  ·  86+13733879582  ·  1624271942@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Chinese Academy of Medical Sciences,Peking Union Medical College HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07014150