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Study identifier: NCT07011576 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

Condition: Colon Cancer · Rectal Cancer · Colorectal Cancer  ·  Sponsor: SCRI Development Innovations, LLC

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label multicenter, single-arm Phase II study of Fruquintinib in combination with FOLFIRI (leucovorin calcium (folinic acid), fluorouracil, and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to: * Evaluate the efficacy of the combination of fruquintinib + FOLFIRI in the 2nd-line mCRC setting * Evaluate the safety of the combination of fruquintinib + FOLFIRI

This description comes directly from the study's public registry record.

Talk to the study team

Sarah Cannon Sarah Cannon Development Innovations, LLC  ·  844-710-6157  ·  SCRI.InnovationsMedical@scri.com

Always discuss trial participation with your own doctor first.

Locations (14)

Rocky Mountain Cancer Center - PrimaryDenver, Colorado, United StatesRecruiting
Illinois Cancer SpecialistsArlington Heights, Illinois, United StatesRecruiting
Maryland Oncology HematologyColumbia, Maryland, United StatesRecruiting
Minnesota Oncology Hematology - PrimaryMaple Grove, Minnesota, United StatesRecruiting
Missouri Cancer AssociatesColumbia, Missouri, United StatesRecruiting
Oncology Associates of Oregon - PrimaryEugene, Oregon, United StatesRecruiting
Northwest Cancer Specialists - CompassPortland, Oregon, United StatesRecruiting
Alliance Cancer SpecialistsWynnewood, Pennsylvania, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting
Texas Oncology - Central/South TexasAustin, Texas, United StatesRecruiting
Texas Oncology - Gulf CoastBeaumont, Texas, United StatesRecruiting
Texas Oncology - Northeast TexasTyler, Texas, United StatesRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07011576