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Study identifier: NCT07009509 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping

Condition: Nicotine Vaping  ·  Sponsor: University of Colorado, Denver

PhaseNA
Planned participants1166
Who can joinAll sexes, 9 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this pilot study is to determine the feasibility of a randomized trial of the YES-CAN! (Youth Engaged Strategies to Change Adolescent Norms) program to prevent nicotine vaping among adolescents. The program integrates the following evidence-based strategies: youth-adult collaboration; youth-developed narrative videos to convey health messages; peer leaders as change agents; and sustained implementation to change the normative environment. Two middle/high school communities will receive the YES-CAN! intervention. In each school community, a trained teacher will deliver a credit-earning middle or high school class to 25-30 middle or high school students, who will produce 6-8 short videos intended to increase refusal skills; promote stress management and positive coping; change social norms; prevent vaping initiation; and promote vaping cessation among current users. Videos will use a narrative approach and integrate known determinants of vaping. Middle or high school students will collaborate with the teacher and researchers to develop discussion guides and skills-building activities based on best practices for substance use prevention. In 6-8 sessions, middle or high school students will deliver their videos to all students in the associated middle school. A text messaging or other media component will reinforce and boost the effectiveness of the classroom sessions. Aims for this pilot/feasibility study are: 1. To determine the feasibility and acceptability of im…

This description comes directly from the study's public registry record.

Talk to the study team

Lori A Crane, PhD, MPH  ·  3037244385  ·  lori.crane@cuanschutz.edu

Nancy L Asdigian, PhD  ·  7203243748  ·  nancy.asdigian@cuanschutz.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Colorado Anschutz Medical CampusAurora, Colorado, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07009509