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Study identifier: NCT07008456 Synced from ClinicalTrials.gov · July 29, 2026
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A Study to Investigate the Efficacy and Safety of Two Different Doses of Twice Daily Distal Jejunal-release Dextrose Beads Formulations Combined With a Gel Composition Compared to Placebos in Obese Subjects With Weight Related Comorbidities

Condition: Obese With Comorbidities · Obese Patients (BMI ≥ 30 kg/m²)  ·  Sponsor: Aphaia Pharma US LLC

PhasePhase 2
Planned participants102
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this randomized, double-blind, placebo-controlled, phase IIa study is to demonstrate superiority on body weight reduction of two different doses of twice daily distal jejunal-release dextrose beads formulations (APHD 012 and APHD 002) combined with a gel composition, compared with two different doses of the placebo beads formulations (APHP 012 and APHD 002) combined with a gel composition in obese subjects with weight related comorbidities.

This description comes directly from the study's public registry record.

Talk to the study team

Steffen S Bolz, Prof. (Univ. Toronto) Dr. med.  ·  +41/41/78496331  ·  bolz@aphaiapharma.com

Susanne K Grafe, MD  ·  +41/41/78496331  ·  grafe@aphaiapharma.com

Always discuss trial participation with your own doctor first.

Locations (6)

LTD "Israeli-Georgian Medical Research Clinic Healthycore"Tbilisi, K'alak'i T'bilisi, GeorgiaRecruiting
LTD "New Hospitals"Tbilisi, K'alak'i T'bilisi, GeorgiaRecruiting
LTD "Acad. G. Chapidze Emergency Cardiology Center"Tbilisi, K'alak'i T'bilisi, GeorgiaRecruiting
LTD "Diacor"Tbilisi, K'alak'i T'bilisi, GeorgiaRecruiting
NNLE "Jo Ann University Hospital"Tbilisi, K'alak'i T'bilisi, GeorgiaRecruiting
LTD The First Medical CenterTbilisi, K'alak'i T'bilisi, GeorgiaRecruiting

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Source record: clinicaltrials.gov/study/NCT07008456