Condition: Acute Appendicitis · Acute Appendicitis With Rupture · Abdominal Pain (AP) · Sponsor: KBC Split
Diagnosing acute appendicitis in children remains a clinical challenge, with delayed or incorrect diagnosis potentially leading to serious complications or unnecessary surgery. Prostaglandin E urinary metabolites (PGE-M) have been found elevated in various inflammatory conditions, but their diagnostic value in pediatric appendicitis is not well established. This study aims to assess the potential of PGE-M as a biomarker for acute appendicitis in children. The study will be conducted over 12 months and will include 100 children aged 5 to 17 years presenting with acute abdominal pain. In addition to routine laboratory tests, urinary PGE-M levels will be analyzed. The study involves minimal risk to participants
This description comes directly from the study's public registry record.
Tomislav Žuvela, Doctor of Medicine, MD · +385919008148 · tomislav.zuvela29@gmail.com
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| University Hospital of Split | Split, Croatia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07008092