Condition: Breast Cancer, Metastatic · Sponsor: ALX Oncology Inc.
The Substudy Protocol ASPEN-09-03 is a Phase 2, single-arm, multicenter study evaluating the efficacy, safety, and tolerability of evorpacept in combination with trastuzumab and chemotherapy in participants with HER2-positive metastatic breast cancer who have previously received trastuzumab-deruxtecan. This substudy is actively recruiting. ASPEN-09-03 is a substudy under Master Protocol ASPEN-09, and additional substudies are as follows: * Metastatic colorectal cancer (CRC) - dose escalation phase to evaluate evorpacept in combination with other drugs. This substudy is not open. * Recurrent/metastatic head and neck cancer (HNSCC) - dose escalation phase to evaluate evorpacept in combination with other drugs. This substudy is not open.
This description comes directly from the study's public registry record.
Cheng Quah, MD · 650-466-7125 · info@alxoncology.com
Always discuss trial participation with your own doctor first.
| The University of Arizona Cancer Center - North Campus | Tucson, Arizona, United States | Recruiting |
| City of Hope | Duarte, California, United States | Recruiting |
| UC San Diego Moores Cancer Center | La Jolla, California, United States | Recruiting |
| UC Irvine Health - Chao Family Comprehensive Cancer Center | Orange, California, United States | Recruiting |
| Saint Joseph Hospital - Cancer Centers of Colorado | Denver, Colorado, United States | Recruiting |
| Lutheran Hospital - Cancer Centers of Colorado | Golden, Colorado, United States | Recruiting |
| Saint Mary's Regional Hospital - Cancer Centers of Colorado | Grand Junction, Colorado, United States | Recruiting |
| The George Washington Medical facility Associates | Washington D.C., District of Columbia, United States | Recruiting |
| Sylvester Comprehensive Cancer Center | Miami, Florida, United States | Recruiting |
| City of Hope Chicago | Zion, Illinois, United States | Recruiting |
| University of Michigan Rogel Cancer Center | Ann Arbor, Michigan, United States | Recruiting |
| HealthPartners Frauenshuh Cancer Center | Saint Louis Park, Minnesota, United States | Recruiting |
+ 32 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07007559