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Study identifier: NCT07007143 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication for Oral Anticoagulant

Condition: Mitral Regurgitation  ·  Sponsor: Chinese Academy of Medical Sciences, Fuwai Hospital

PhasePhase 4
Planned participants1032
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

Mitral regurgitation (MR) is the most common valvular heart disease, affecting approximately 24.2 million people worldwide (with a higher prevalence in older age groups). Transcatheter edge-to-edge repair (TEER) is now a well-established strategy in high-risk patients with MR. Globally, over 250,000 patients have benefited from the TEER technique. However, no dedicated study has prospectively evaluated different antithrombotic strategies following TEER in patients undergone TEER procedure. Current guidelines do not provide any recommendations for the antithrombotic management of TEER. Consequently, considerable treatment variation exists in clinical studies and practice. The investigators will conduct a multicenter, open-label randomized trial to compare different antithrombotic strategies following TEER in patients without an indication for OAC.

This description comes directly from the study's public registry record.

Talk to the study team

Xiangbin Pan, MD,PhD  ·  +86(10)88396666  ·  panxiangbin@fuwaihospital.org

Zizheng Liu, M.B  ·  +86(10)88396666  ·  liuzizheng00@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Chinese Academy of Medical Sciences, Fuwai HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07007143