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Study identifier: NCT07006064 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Preventing Hypoxia in Sedated TAVI: SuperNO₂VA vs. Conventional Oxygen

Condition: Aortic Stenosis  ·  Sponsor: Ankara Bilkent Sehir Hastanesi

PhaseNA
Planned participants100
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

With increasing life expectancy, the geriatric population continues to grow. According to the Turkish Statistical Institute (TÜİK), the average life expectancy in Turkey between 2021 and 2023 is 77.3 years. As the number of elderly surgical patients rises, optimizing anesthesia care is critical to reducing complications and improving clinical outcomes. In elderly patients with severe aortic stenosis, traditional surgical aortic valve replacement poses a high risk of complications. Consequently, Transcatheter Aortic Valve Implantation (TAVI) has emerged as a preferred, less invasive alternative. Due to technological advancements and shorter procedure durations, TAVI is increasingly performed under sedation rather than general anesthesia. However, sedation carries risks, including hypoxemia and hypoventilation, primarily due to sedative-induced respiratory depression. Pulse oximetry, the traditional monitoring method, measures only peripheral oxygen saturation and does not provide early detection of apnea or hypoventilation. Therefore, monitoring end-tidal carbon dioxide (EtCO₂) during sedation has gained importance. The American Society of Anesthesiologists (ASA) recommends EtCO₂ monitoring during sedation. However, obtaining accurate EtCO₂ values via nasal cannulas is technically challenging. Open sampling ports and high oxygen flow rates can cause dilution or loss of exhaled CO₂, resulting in inaccurate readings. The SuperNO₂VA™ nasal mask (Vyaire Medical, USA) addresses t…

This description comes directly from the study's public registry record.

Talk to the study team

Muhammed T Daşgın  ·  +90 541 2098225  ·  m.talhadasgin@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ankara Bilkent City HospitalAnkara, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07006064