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Study identifier: NCT07005323 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Progression Suppression and Retinal Regression in VEGF-resistant AMD

Condition: Neovascular Age-related Macular Degeneration (AMD)  ·  Sponsor: PharmaBio Corporation

PhaseNA
Planned participants10
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to assess safety and efficacy in patients with Neovascular Age-related Macular Degeneration with no response to existing therapy. The main measures it aims to answer are: * Investigation of adverse events * Changes in clinical testing data * Changes in vital signs * Changes in intraocular pressure of the therapeutic eye * Changes in testing of anterior segment of the therapeutic eye Participants will be implanted one sheet of PAL-222 into the subretinal space through pars plana vitrectomy. Researchers will compare pre and post implantation of therapeutic eye to see if any safety issues recognized

This description comes directly from the study's public registry record.

Talk to the study team

Hitoshi Hitoshi Kusano, M.D.  ·  +81 44-589-6479  ·  clinicaltrial@pharmabio.co.jp

Always discuss trial participation with your own doctor first.

Locations (1)

Yamaguchi University HospitalUbe, Ymaguchi, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT07005323