Condition: Bloodstream Infection · Ventilator Associated Bacterial Pneumonia · Hospital Acquired Bacterial Pneumonia · Sponsor: National University of Singapore
TREAT-GNB is an innovative trial to expedite the evaluation of various antibiotic choices and treatment strategies for severe multidrug-resistant Gram-negative bacterial infections, specifically bloodstream and lower respiratory tract infections. This approach combines platform trial elements with adaptive clinical designs to streamline the evaluation of various treatment options and optimise resource utilisation. The overall aim of the TREAT-GNB platform trial is to identify interventions that improve survival in patients with severe infections due to Gram-negative bacteria. In the CR-GNB silo of TREAT-GNB, the primary objective is to quantify the effect on all-cause mortality at 28 days of a range of interventions in patients with bloodstream infections, ventilator-associated pneumonia, and hospital-acquired pneumonia caused by CR-GNB.
This description comes directly from the study's public registry record.
Yin Mo, MBBS, PhD · +65 65164988 · mdcmy@nus.edu.sg
Always discuss trial participation with your own doctor first.
| Royal Brisbane and Women's Hospital | Brisbane, Queensland, Australia | Not Yet Recruiting |
| Princess Alexandra Hospital | Brisbane, Australia | Not Yet Recruiting |
| The First Affiliated Hospital, Zhejiang University School of Medicine | Hangzhou, China | Not Yet Recruiting |
| The Second Affiliated Hospital, Xi'an Jiang Tong University | Xi'an, China | Not Yet Recruiting |
| Xuzhou First People's Hospital | Xuzhou, China | Not Yet Recruiting |
| American University of Beirut Medical Center | Beirut, Lebanon | Not Yet Recruiting |
| Queen Elizabeth I | Kota Kinabalu, Sabah, Malaysia | Not Yet Recruiting |
| Queen Elizabeth II | Kota Kinabalu, Sabah, Malaysia | Not Yet Recruiting |
| Miri Sarawak Hospital | Miri, Sarawak, Malaysia | Not Yet Recruiting |
| Ampang Hospital | Ampang, Selangor, Malaysia | Not Yet Recruiting |
| Hospital Sungai Buloh | Sungai Buloh, Selangor, Malaysia | Not Yet Recruiting |
| Hamad Medical Corporation | Doha, Qatar | Not Yet Recruiting |
+ 29 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07004049