Condition: Gastrointestinal Disease · Sponsor: Harbin Medical University
The objective of this clinical trial is to assess the feasibility of the remimazolam combined with esketamine OFA (opioid-free anesthesia) protocol for painless gastroscopy and colonoscopy in elderly patients and to determine if it is non-inferior to the traditional OA (opioid-containing anesthesia) protocol. The main questions it aims to answer are: * Is the remimazolam combined with esketamine protocol feasible for painless gastroscopy and colonoscopy in elderly patients? * Is the OFA protocol superior to the OA protocol? Participants will: * During anesthesia induction, the experimental group will receive remimazolam combined with esketamine for anesthesia, while the control group will receive remimazolam combined with remifentanil. * Record respiratory and circulatory indicators and adverse reaction times.
This description comes directly from the study's public registry record.
LIU Shujie LIU · +86 138 4508 0390 · shujieliu312@163.com
SHI Xiaoqian SHI · +86 188 3424 7923 · shixiaoqian005@163.com
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| The First Affiliated Hospital of Harbin Medical University | Harbin, Heilongjiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07002801