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Study identifier: NCT07000383 Synced from ClinicalTrials.gov · July 29, 2026
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Evaluation of the Efficacy and Safety of Gelsectan in the Treatment of Diarrhea-predominant Irritable Bowel Syndrome

Condition: Diarrhea-predominant Irritable Bowel Syndrome · Irritable Bowel Syndrome of Diarrhea Type (IBS-D)  ·  Sponsor: University Medical Center Ho Chi Minh City (UMC)

PhaseNA
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical study aims to investigate the effectiveness and safety of Gelsectan, a treatment containing xyloglucan, in adults diagnosed with diarrhea-predominant irritable bowel syndrome (IBS-D) in Vietnam. IBS-D is a common digestive disorder that causes frequent diarrhea along with abdominal pain and bloating, significantly affecting patients' daily life and wellbeing. The main goal of the study is to determine whether Gelsectan can reduce the severity of symptoms such as diarrhea, abdominal discomfort, and bloating, and improve patients' quality of life. Participants will be randomly assigned to receive either Gelsectan alone, Gelsectan combined with an antispasmodic medication, or antispasmodic medication alone. The treatment will last for two months, with regular monitoring of symptom changes and any side effects. The investigators hypothesize that Gelsectan treatment will lead to better symptom relief and quality of life compared to standard antispasmodic treatment. The study will also carefully observe the safety profile of Gelsectan during the treatment period. Results from this study will provide important information about the potential benefits and risks of Gelsectan for Vietnamese patients with IBS-D and may contribute to improving treatment options for this condition in Vietnam.

This description comes directly from the study's public registry record.

Talk to the study team

Assoc. Professor. Thong Duy Vo, M.D. Ph.D.  ·  +84 932039888  ·  thong.vd@umc.edu.vn

Qui Huu Nguyen, M.D.  ·  +84 975560142  ·  qui.nh@umc.edu.vn

Always discuss trial participation with your own doctor first.

Locations (1)

University Medical Center Ho Chi Minh CityHo Chi Minh City, District 5, VietnamRecruiting

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Source record: clinicaltrials.gov/study/NCT07000383