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Study identifier: NCT06999603 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Condition: Viral Pneumonia  ·  Sponsor: Synairgen Research Ltd.

PhasePhase 2
Planned participants550
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this Phase 2 study is to assess about the safety, antiviral biomarker responses and efficacy of SNG001 when given to patients requiring invasive mechanical ventilation due to a respiratory virus infection. Its ability to speed up virus clearance and reduce mortality, compared with standard of care, will be studied. The study is split into two parts. All participants will receive standard of care in addition to SNG001 or placebo. In Part 1, the safety of SNG001 will be assessed. Participants of 50 years and older will receive study drug or placebo once a day for up to 14 days, whilst in hospital. In Part 2, the primary objective will be the efficacy of SNG001. Participants between 18 and 50 years with an immunocompromising condition and patients over 50 years (with or without an immunocompromising condition) will receive study drug once a day for up to 14 days, whilst in hospital.

This description comes directly from the study's public registry record.

Talk to the study team

Sophie Hemmings  ·  +442380512800  ·  submissions@synairgen.com

Always discuss trial participation with your own doctor first.

Locations (67)

University of California - DavisSacramento, California, United StatesNot Yet Recruiting
Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical CenterTorrance, California, United StatesRecruiting
NCH Pulmonary Critical CareNaples, Florida, United StatesNot Yet Recruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Snake River Research, PLLCIdaho Falls, Idaho, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
Sinai-Grace HospitalDetroit, Michigan, United StatesRecruiting
William Beaumont HospitalRoyal Oak, Michigan, United StatesRecruiting
Mayo Clinic - RochesterRochester, Minnesota, United StatesRecruiting
Washington University in St. LouisSt Louis, Missouri, United StatesRecruiting
VA Western New York Healthcare systemBuffalo, New York, United StatesNot Yet Recruiting
NYU Langone Tisch HospitalNew York, New York, United StatesNot Yet Recruiting

+ 55 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06999603