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Study identifier: NCT06998966 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Optimizing Proton Pump Inhibitors (PPI) Prescribing With EHR-Based Decision Support

Condition: Prescribing Patterns, Physician · Physician's Practice Patterns · Drug Utilization Review  ·  Sponsor: University of California, Los Angeles

PhaseNA
Planned participants372
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

The proposed study is a quality improvement initiative designed to rigorously evaluate new variations of UCLA Health's proton pump inhibitor (PPI) order panels, building on internal quality improvement efforts to optimize prescribing workflows within the Electronic Health Record (EHR). PPIs are notoriously overprescribed, and the study team has identified that the CareConnect default prescription setting of 90 days with three refills (360 pill days) exceed standard guidelines (in most cases, 60 pill days). It is unclear whether this is the most appropriate workflow. Given that deprescribing PPIs carries minimal risk for most patients, this initiative will assess whether modifying defaulted prescription lengths influences prescribing behavior while ensuring physicians retain full decision-making authority. This evaluation of PPI order panel variations is embedded within UCLA's existing EHR system, ensuring that changes are tested pragmatically within routine workflows. The study aims to determine whether small adjustments to the order panel can better align prescribing patterns with clinical best practices while maintaining physician autonomy.

This description comes directly from the study's public registry record.

Talk to the study team

Katelyn Clinical Research Coordinator  ·  310-267-5250  ·  katenguyen@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCLA Health SystemLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06998966