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Study identifier: NCT06997419 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Dexamethasone Palmitate for PONV After Open Surgery

Condition: Postoperative Nausea and Vomiting · Dexamethasone Palmitate · Open Surgery  ·  Sponsor: Beijing Tiantan Hospital

PhaseNA
Planned participants500
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

Dexamethasone is almost one of the most commonly used drugs for postoperative nausea and vomiting (PONV) prevention. However, PONV is still a complex problem to be solved; for example, even with preoperative dexamethasone administration, there are still some patients still experience PONV within 24 hours postoperatively. Compared to dexamethasone, dexamethasone palmitate has a long-lasting anti-inflammatory effect, 2-5 times that of traditional water-soluble dexamethasone, with fewer adverse effects. This trial aims to assess the effect and safety of preoperative dexamethasone palmitate on PONV after open surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Fang Luo  ·  59976661  ·  13611326978@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fang LuoBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06997419