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Study identifier: NCT06996951 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy

Condition: Cystic Fibrosis (CF) · Chronic Rhinosinusitis (CRS)  ·  Sponsor: Indiana University

PhasePhase 3
Planned participants64
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The investigators are doing this study to discover if it is appropriate for people with Cystic Fibrosis (CF) on highly effective modulator therapy (HEMT) to stop using certain standard Sino nasal therapies such as high-volume nasal saline irrigations, topical nasal steroids, and topical nasal antibiotics. They are also going to study the fluid inside the nose to see if there are changes when stopping these therapies. Right now, they are not sure if it is suggested to stop these treatments when patients begin highly effective modulator therapy (HEMT)

This description comes directly from the study's public registry record.

Talk to the study team

Elisa Illing, MD  ·  317-944-6467  ·  eilling@iu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Indiana University HealthIndianapolis, Indiana, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06996951